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Specificity, Safety, Efficacy of EGFRvIII-Retargeted Oncolytic HSV for Xenotransplanted Human Glioblastoma

Glioblastoma is a lethal primary brain tumor lacking effective therapy. The secluded onset site, combined with the infiltrative properties of this tumor, require novel targeted therapies. In this scenario, the use of oncolytic viruses retargeted to glioblastoma cells and able to spread across the tu...

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Detalles Bibliográficos
Autores principales: Appolloni, Irene, Alessandrini, Francesco, Menotti, Laura, Avitabile, Elisa, Marubbi, Daniela, Piga, Noemi, Ceresa, Davide, Piaggio, Francesca, Campadelli-Fiume, Gabriella, Malatesta, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473268/
https://www.ncbi.nlm.nih.gov/pubmed/34578259
http://dx.doi.org/10.3390/v13091677

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