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Specificity, Safety, Efficacy of EGFRvIII-Retargeted Oncolytic HSV for Xenotransplanted Human Glioblastoma
Glioblastoma is a lethal primary brain tumor lacking effective therapy. The secluded onset site, combined with the infiltrative properties of this tumor, require novel targeted therapies. In this scenario, the use of oncolytic viruses retargeted to glioblastoma cells and able to spread across the tu...
Autores principales: | Appolloni, Irene, Alessandrini, Francesco, Menotti, Laura, Avitabile, Elisa, Marubbi, Daniela, Piga, Noemi, Ceresa, Davide, Piaggio, Francesca, Campadelli-Fiume, Gabriella, Malatesta, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473268/ https://www.ncbi.nlm.nih.gov/pubmed/34578259 http://dx.doi.org/10.3390/v13091677 |
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