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Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod

Vidutolimod, also known as CMP-001, is a virus-like particle composed of the Qβ bacteriophage coat protein encasing a TLR9 agonist. Vidutolimod injected intratumorally is showing promise in early phase clinical trials based on its ability to alter the tumor microenvironment and induce an anti-tumor...

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Detalles Bibliográficos
Autores principales: Sabree, Shakoora A., Lemke-Miltner, Caitlin D., Blackwell, Sue E., Yin, Chaobo, Bossler, Aaron, Ebeid, Kareem, Salem, Aliasger K., Weiner, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473335/
https://www.ncbi.nlm.nih.gov/pubmed/34579220
http://dx.doi.org/10.3390/vaccines9090982