Cargando…

Venom peptides – A comprehensive translational perspective in pain management

Venom peptides have been evolving complex therapeutic interventions that potently and selectively modulate a range of targets such as ion channels, receptors, and signaling pathways of physiological processes making it potential therapeutic. Several venom peptides were deduced in vivo for clinical d...

Descripción completa

Detalles Bibliográficos
Autores principales: V, Vidya, Achar, Raghu Ram, M.U, Himathi, N, Akshita, T, Yogish Somayaji, Kameshwar, Vivek Hamse, Byrappa, K., Ramadas, Dinesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473576/
https://www.ncbi.nlm.nih.gov/pubmed/34604795
http://dx.doi.org/10.1016/j.crtox.2021.09.001
Descripción
Sumario:Venom peptides have been evolving complex therapeutic interventions that potently and selectively modulate a range of targets such as ion channels, receptors, and signaling pathways of physiological processes making it potential therapeutic. Several venom peptides were deduced in vivo for clinical development targeting pain management, diabetes, cardiovascular diseases, antimicrobial activity. Several contributions have been detailed for a clear perspective for a better understanding of venomous animals, their venom, and their pharmacological effects. Here we unravel and summarize the recent advances in wide venom peptides across varieties of species for their therapeutics prospects.