Acute and chronic effects of a light-activated FGF receptor in keratinocytes in vitro and in mice

FGFs and their high-affinity receptors (FGFRs) play key roles in development, tissue repair, and disease. Because FGFRs bind overlapping sets of ligands, their individual functions cannot be determined using ligand stimulation. Here, we generated a light-activated FGFR2 variant (OptoR2) to selective...

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Detalles Bibliográficos
Autores principales: Rauschendorfer, Theresa, Gurri, Selina, Heggli, Irina, Maddaluno, Luigi, Meyer, Michael, Inglés-Prieto, Álvaro, Janovjak, Harald, Werner, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473723/
https://www.ncbi.nlm.nih.gov/pubmed/34548382
http://dx.doi.org/10.26508/lsa.202101100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473723/
https://www.ncbi.nlm.nih.gov/pubmed/34548382
http://dx.doi.org/10.26508/lsa.202101100

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