A highly multiplexed quantitative phosphosite assay for biology and preclinical studies

Reliable methods to quantify dynamic signaling changes across diverse pathways are needed to better understand the effects of disease and drug treatment in cells and tissues but are presently lacking. Here, we present SigPath, a targeted mass spectrometry (MS) assay that measures 284 phosphosites in...

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Detalles Bibliográficos
Autores principales: Keshishian, Hasmik, McDonald, E Robert, Mundt, Filip, Melanson, Randy, Krug, Karsten, Porter, Dale A, Wallace, Luke, Forestier, Dominique, Rabasha, Bokang, Marlow, Sara E, Jane‐Valbuena, Judit, Todres, Ellen, Specht, Harrison, Robinson, Margaret Lea, Jean Beltran, Pierre M, Babur, Ozgun, Olive, Meagan E, Golji, Javad, Kuhn, Eric, Burgess, Michael, MacMullan, Melanie A, Rejtar, Tomas, Wang, Karen, Mani, DR, Satpathy, Shankha, Gillette, Michael A, Sellers, William R, Carr, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474009/
https://www.ncbi.nlm.nih.gov/pubmed/34569154
http://dx.doi.org/10.15252/msb.202010156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474009/
https://www.ncbi.nlm.nih.gov/pubmed/34569154
http://dx.doi.org/10.15252/msb.202010156

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