Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives

Great progress has been made in the tandem annulation of enynes in the past few years. This review only presents the corresponding reactions of 1,3-enyne structural motifs to provide the functionalized pyridine and pyrrole derivatives. The functionalization reactions cover iodination, bromination, t...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Luo, Puying, Fu, Yang, Hao, Tianxin, Liu, Xuan, Ding, Qiuping, Peng, Yiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474070/
https://www.ncbi.nlm.nih.gov/pubmed/34630726
http://dx.doi.org/10.3762/bjoc.17.163
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author Liu, Yi
Luo, Puying
Fu, Yang
Hao, Tianxin
Liu, Xuan
Ding, Qiuping
Peng, Yiyuan
author_facet Liu, Yi
Luo, Puying
Fu, Yang
Hao, Tianxin
Liu, Xuan
Ding, Qiuping
Peng, Yiyuan
author_sort Liu, Yi
collection PubMed
description Great progress has been made in the tandem annulation of enynes in the past few years. This review only presents the corresponding reactions of 1,3-enyne structural motifs to provide the functionalized pyridine and pyrrole derivatives. The functionalization reactions cover iodination, bromination, trifluoromethylation, azidation, carbonylation, arylation, alkylation, selenylation, sulfenylation, amidation, esterification, and hydroxylation. We also briefly introduce the applications of the products and the reaction mechanisms for the synthesis of corresponding N-heterocycles.
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spelling pubmed-84740702021-10-07 Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives Liu, Yi Luo, Puying Fu, Yang Hao, Tianxin Liu, Xuan Ding, Qiuping Peng, Yiyuan Beilstein J Org Chem Review Great progress has been made in the tandem annulation of enynes in the past few years. This review only presents the corresponding reactions of 1,3-enyne structural motifs to provide the functionalized pyridine and pyrrole derivatives. The functionalization reactions cover iodination, bromination, trifluoromethylation, azidation, carbonylation, arylation, alkylation, selenylation, sulfenylation, amidation, esterification, and hydroxylation. We also briefly introduce the applications of the products and the reaction mechanisms for the synthesis of corresponding N-heterocycles. Beilstein-Institut 2021-09-22 /pmc/articles/PMC8474070/ /pubmed/34630726 http://dx.doi.org/10.3762/bjoc.17.163 Text en Copyright © 2021, Liu et al. https://creativecommons.org/licenses/by/4.0/https://www.beilstein-journals.org/bjoc/terms/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). Please note that the reuse, redistribution and reproduction in particular requires that the author(s) and source are credited and that individual graphics may be subject to special legal provisions. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms/terms)
spellingShingle Review
Liu, Yi
Luo, Puying
Fu, Yang
Hao, Tianxin
Liu, Xuan
Ding, Qiuping
Peng, Yiyuan
Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
title Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
title_full Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
title_fullStr Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
title_full_unstemmed Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
title_short Recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
title_sort recent advances in the tandem annulation of 1,3-enynes to functionalized pyridine and pyrrole derivatives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474070/
https://www.ncbi.nlm.nih.gov/pubmed/34630726
http://dx.doi.org/10.3762/bjoc.17.163
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