Cargando…

The origin and nature of the complex autoantibody profile in cerebrospinal fluid

The present study demonstrates, using human protein microarrays and plasma and cerebrospinal fluid samples obtained pre-surgically and simultaneously from 46 hip fracture repair patients, that CSF exhibits an extraordinarily complex IgG autoantibody profile composed of thousands of autoantibodies. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kheirkhah, Rahil, DeMarshall, Cassandra, Sieber, Frederick, Oh, Esther, Nagele, Robert G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474157/ http://dx.doi.org/10.1016/j.bbih.2019.100032

Ejemplares similares

Detection of early-stage Alzheimer’s pathology using blood-based autoantibody biomarkers in elderly hip fracture repair patients
por: DeMarshall, Cassandra, et al.
Publicado: (2019)

Diagnosis of Alzheimer's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera
por: Nagele, Eric, et al.
Publicado: (2011)

Diagnosis of Parkinson's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera
por: Han, Min, et al.
Publicado: (2012)

Natural IgG Autoantibodies Are Abundant and Ubiquitous in Human Sera, and Their Number Is Influenced By Age, Gender, and Disease
por: Nagele, Eric P., et al.
Publicado: (2013)

Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients – A validation study in plasma and cerebrospinal fluid from two Swedish cohorts
por: Bynke, Annie, et al.
Publicado: (2020)

Dementia-associated changes of immune cell composition within the cerebrospinal fluid
por: Busse, Stefan, et al.
Publicado: (2021)

Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid
por: Royds, Jonathan, et al.
Publicado: (2020)

Detection of Alzheimer's disease at mild cognitive impairment and disease progression using autoantibodies as blood-based biomarkers
por: DeMarshall, Cassandra A., et al.
Publicado: (2016)

Synapsin autoantibodies during pregnancy are associated with fetal abnormalities
por: Bünger, Isabel, et al.
Publicado: (2023)

Immunity and autoantibodies of a mouse strain with autistic-like behavior
por: Uddin, Mohammad Nizam, et al.
Publicado: (2020)

CCR6(+) Th cells in the cerebrospinal fluid of persons with multiple sclerosis are dominated by pathogenic non-classic Th1 cells and GM-CSF-only-secreting Th cells
por: Restorick, S.M., et al.
Publicado: (2017)

Early Detection of Alzheimer’s Disease-Related Pathology Using a Multi-Disease Diagnostic Platform Employing Autoantibodies as Blood-Based Biomarkers
por: DeMarshall, Cassandra A., et al.
Publicado: (2023)

An examination of plasma autoantibodies against voltage gated calcium channels in schizophrenia
por: McLean, Ryan Thomas, et al.
Publicado: (2023)

Immunoreactivity to astrocytes in different forms of dementia: High prevalence of autoantibodies to GFAP
por: Barthel, Paula Charlotte, et al.
Publicado: (2023)

Anticancer Effect of Enterococcus faecium, Isolated from Vaginal Fluid, on Ovarian Cancer Cells
por: Pourmollaei, Soraya, et al.
Publicado: (2023)

Evidence that Brain-Reactive Autoantibodies Contribute to Chronic Neuronal Internalization of Exogenous Amyloid-β(1-42) and Key Cell Surface Proteins During Alzheimer’s Disease Pathogenesis
por: Goldwaser, Eric L., et al.
Publicado: (2020)

Autoantibody-associated psychiatric symptoms and syndromes in adults: A narrative review and proposed diagnostic approach
por: Hansen, Niels, et al.
Publicado: (2020)

Immunoglobulin E and G autoantibodies against eosinophil proteins in children and adults with asthma and healthy subjects
por: Sánchez, Jorge, et al.
Publicado: (2023)

Systemic and cerebrospinal fluid immune and complement activation in Ugandan children and adolescents with long‐standing nodding syndrome: A case‐control study
por: Ogwang, Rodney, et al.
Publicado: (2021)

Putative autoantibodies in the cerebrospinal fluid of Alzheimer’s disease patients
por: Lim, Bryant, et al.
Publicado: (2019)

Anti-lysoganglioside and other anti-neuronal autoantibodies in post-treatment Lyme Disease and Erythema Migrans after repeat infection
por: Fallon, Brian A., et al.
Publicado: (2020)

Breakthrough SARS‐CoV‐2 infections in immune mediated disease patients undergoing B cell depleting therapy: A retrospective cohort analysis
por: Calabrese, Cassandra M, et al.
Publicado: (2022)

Particular Distribution of Enterobacter cloacae Strains Isolated from Urinary Tract Infection within Clonal Complexes
por: Akbari, Majid, et al.
Publicado: (2016)

Uniform binding and negative catalysis at the origin of enzymes
por: Noor, Elad, et al.
Publicado: (2022)

Distinct serum and cerebrospinal fluid cytokine and chemokine profiles in autoantibody-associated demyelinating diseases
por: Hofer, Livia S, et al.
Publicado: (2019)

Differential Expression Profile of ZFX Variants Discriminates Breast Cancer Subtypes
por: Pourkeramati, Fatemeh, et al.
Publicado: (2019)

Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin
por: Valenti, Rosario, et al.
Publicado: (2022)

Case Report: Alzheimer's Dementia Associated With Cerebrospinal Fluid Neurochondrin Autoantibodies
por: Hansen, Niels, et al.
Publicado: (2022)

Maturation of biomimetic hydroxyapatite in physiological fluids: a physicochemical and proteomic study
por: Konka, J., et al.
Publicado: (2021)

The impact of Coronavirus (COVID-19) outbreak on faith-based investments: An original analysis
por: Sherif, Mohamed
Publicado: (2020)

Inhibitory Potential of Acroptilon repens against Key Enzymes involved in Alzheimer and Diabetes, Phytochemical Profile, Radical Scavenging, and Antibacterial Activity
por: Afsharnezhad, Moslem, et al.
Publicado: (2021)

Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins
por: Michie, Katharine A., et al.
Publicado: (2023)

Mesenchymal Stem/Stromal-Like Cells from Diploid and Triploid Human Embryonic Stem Cells Display Different Gene Expression Profiles
por: Javidpou, Mahdieh, et al.
Publicado: (2021)

Proteomics Profiling of Chimeric-Truncated Tissue Plasminogen activator Producing- Chinese Hamster Ovary Cells Cultivated in a Chemically Defined Medium Supplemented with Protein Hydrolysates
por: Azarian, Bahareh, et al.
Publicado: (2017)

Autoantibody Profiling on Human Proteome Microarray for Biomarker Discovery in Cerebrospinal Fluid and Sera of Neuropsychiatric Lupus
por: Hu, Chaojun, et al.
Publicado: (2015)

Problematic smartphone use, nature connectedness, and anxiety
por: Richardson, Miles, et al.
Publicado: (2018)

Inhibition of B lymphocyte-induced maturation protein-1 reduces the production of autoantibody and alleviates symptoms of systemic lupus erythematosus
por: Luo, Jie, et al.
Publicado: (2015)

Six autoantibodies associated with autoimmune encephalitis are not detectable in the cerebrospinal fluid of suicide attempters
por: Fernström, Johan, et al.
Publicado: (2017)

High frequency of cerebrospinal fluid autoantibodies in COVID-19 patients with neurological symptoms
por: Franke, Christiana, et al.
Publicado: (2021)

Autoimmune obsessive-compulsive disorder with novel anti-CNS autoantibodies in cerebrospinal fluid
por: Endres, Dominique, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_np0jqsr1i6cakq2l1ha17fndhq