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Maternal high-fat diet modifies myelin organization, microglial interactions, and results in social memory and sensorimotor gating deficits in adolescent mouse offspring

Prenatal exposure to maternal high-fat diet (mHFD) acts as a risk factor for various neurodevelopmental alterations in the progeny. Recent studies in mice revealed that mHFD results in both neuroinflammation and hypomyelination in the exposed offspring. Microglia, the brain-resident macrophages, pla...

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Detalles Bibliográficos
Autores principales: Bordeleau, Maude, Fernández de Cossío, Lourdes, Lacabanne, Chloé, Savage, Julie C., Vernoux, Nathalie, Chakravarty, Mallar, Tremblay, Marie-Ève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474164/
https://www.ncbi.nlm.nih.gov/pubmed/34589781
http://dx.doi.org/10.1016/j.bbih.2021.100281