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Cerebellar mitochondrial dysfunction and concomitant multi-system fatty acid oxidation defects are sufficient to discriminate PTSD-like and resilient male mice
The impact of trauma on mental health is complex with poorly understood underlying mechanisms. Mitochondrial dysfunction is increasingly implicated in psychopathologies and mood disorders, including post-traumatic stress disorder (PTSD). We hypothesized that defects in mitochondrial energy metabolis...
Autores principales: | Preston, Graeme, Emmerzaal, Tim, Kirdar, Faisal, Schrader, Laura, Henckens, Marloes, Morava, Eva, Kozicz, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474165/ https://www.ncbi.nlm.nih.gov/pubmed/34589865 http://dx.doi.org/10.1016/j.bbih.2020.100104 |
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