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Serial Plasma Cell-Free Circulating Tumor DNA Tests Identify Genomic Alterations for Early Prediction of Osimertinib Treatment Outcome in EGFR T790M–Positive NSCLC
INTRODUCTION: Recent advances in the detection of genomic DNA from plasma samples allow us to follow tumor DNA shedding in plasma during systemic treatment. Osimertinib is the standard of care for patients with NSCLC with acquired EGFR T790M mutations. We assessed changes in serial plasma cell-free...
Autores principales: | Liao, Bin-Chi, Hsu, Wei-Hsun, Lee, Jih-Hsiang, Yang, Ching-Yao, Tsai, Tzu-Hsiu, Liao, Wei-Yu, Ho, Chao-Chi, Lin, Chia-Chi, Shih, Jin-Yuan, Yu, Chong-Jen, Soo, Ross A., Yang, James Chih-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474212/ https://www.ncbi.nlm.nih.gov/pubmed/34589970 http://dx.doi.org/10.1016/j.jtocrr.2020.100099 |
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