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Somatic and Germline BRCA 1 and 2 Mutations in Advanced NSCLC From the SAFIR02-Lung Trial
INTRODUCTION: Molecular profiling is considered a standard of care in advanced NSCLC. A comprehensive next-generation sequencing panel can discover somatic or germline BRCA1/2 mutations that are new druggable molecular alterations. However, the phenotypic and potential therapeutic relevance of BRCA1...
Autores principales: | Remon, Jordi, Besse, Benjamin, Leary, Alexandra, Bièche, Ivan, Job, Bastien, Lacroix, Ludovic, Auguste, Aurélie, Mauduit, Marjorie, Audigier-Valette, Clarisse, Raimbourg, Judith, Madroszyk, Anne, Michels, Stefan, Bayar, Mohammed Amine, Jimenez, Marta, Soria, Jean-Charles, Rouleau, Etienne, Barlesi, Fabrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474245/ https://www.ncbi.nlm.nih.gov/pubmed/34589950 http://dx.doi.org/10.1016/j.jtocrr.2020.100068 |
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