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Src-Homology 2 Domain-Containing Phosphatase 2 in Resected EGFR Mutation-Positive Lung Adenocarcinoma
INTRODUCTION: EGFR mutation-positive lung adenocarcinoma (LUAD) displays impaired phosphorylation of ERK and Src-homology 2 domain-containing phosphatase 2 (SHP2) in comparison with EGFR wild-type LUADs. We hypothesize that SHP2 expression could be predictive in patients positive with resected EGFR...
Autores principales: | Ito, Masaoki, Codony-Servat, Jordi, Giménez-Capitán, Ana, Serra-Mitjans, Mireia, Pérez-Ochoa, Francisco, Llige, David, Chaib, Imane, Rami-Porta, Ramón, Obiols, Carme, Call, Sergi, Iglesias, Manuela, Belda-Sanchis, José, Tarroch-Sarasa, Xavier, Karachaliou, Niki, Molina-Vila, Miguel Angel, Okada, Morihito, Rosell, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474259/ https://www.ncbi.nlm.nih.gov/pubmed/34589963 http://dx.doi.org/10.1016/j.jtocrr.2020.100084 |
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