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Oncogenic Fusions May Be Frequently Present at Resistance of EGFR Tyrosine Kinase Inhibitors in Patients With NSCLC: A Brief Report
INTRODUCTION: Despite initial benefit, virtually all patients suffering from EGFR-mutant NSCLC experience acquired resistance to tyrosine kinase inhibitors (TKIs), driven by multiple mechanisms. Recent reports have identified oncogenic kinase fusions as off-target resistance mechanisms; however, the...
Autores principales: | Enrico, Diego, Lacroix, Ludovic, Chen, Jeanne, Rouleau, Etienne, Scoazec, Jean-Yves, Loriot, Yohann, Tselikas, Lambros, Jovelet, Cécile, Planchard, David, Gazzah, Anas, Mezquita, Laura, Ngo-Camus, Maud, Michiels, Stefan, Massard, Christophe, Recondo, Gonzalo, Facchinetti, Francesco, Remon, Jordi, Soria, Jean-Charles, André, Fabrice, Vassal, Gilles, Friboulet, Luc, Besse, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474286/ https://www.ncbi.nlm.nih.gov/pubmed/34589930 http://dx.doi.org/10.1016/j.jtocrr.2020.100023 |
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