The role of gut mycobiome in health and diseases

The gut microbiome comprised of microbes from multiple kingdoms, including bacteria, fungi, and viruses. Emerging evidence suggests that the intestinal fungi (the gut “mycobiome”) play an important role in host immunity and inflammation. Advances in next generation sequencing methods to study the fu...

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Autores principales: Zhang, Lin, Zhan, Hui, Xu, Wenye, Yan, Shuai, Ng, Siew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Prospects and Challenges into the Role of Gut Microbiome in Health and Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474302/
https://www.ncbi.nlm.nih.gov/pubmed/34589139
http://dx.doi.org/10.1177/17562848211047130
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author Zhang, Lin
Zhan, Hui
Xu, Wenye
Yan, Shuai
Ng, Siew C.
author_facet Zhang, Lin
Zhan, Hui
Xu, Wenye
Yan, Shuai
Ng, Siew C.
author_sort Zhang, Lin
collection PubMed
description The gut microbiome comprised of microbes from multiple kingdoms, including bacteria, fungi, and viruses. Emerging evidence suggests that the intestinal fungi (the gut “mycobiome”) play an important role in host immunity and inflammation. Advances in next generation sequencing methods to study the fungi in fecal samples and mucosa tissues have expanded our understanding of gut fungi in intestinal homeostasis and systemic immunity in health and their contribution to different human diseases. In this review, the current status of gut mycobiome in health, early life, and different diseases including inflammatory bowel disease, colorectal cancer, and metabolic diseases were summarized.
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spelling pubmed-84743022021-09-28 The role of gut mycobiome in health and diseases Zhang, Lin Zhan, Hui Xu, Wenye Yan, Shuai Ng, Siew C. Therap Adv Gastroenterol Prospects and Challenges into the Role of Gut Microbiome in Health and Disease The gut microbiome comprised of microbes from multiple kingdoms, including bacteria, fungi, and viruses. Emerging evidence suggests that the intestinal fungi (the gut “mycobiome”) play an important role in host immunity and inflammation. Advances in next generation sequencing methods to study the fungi in fecal samples and mucosa tissues have expanded our understanding of gut fungi in intestinal homeostasis and systemic immunity in health and their contribution to different human diseases. In this review, the current status of gut mycobiome in health, early life, and different diseases including inflammatory bowel disease, colorectal cancer, and metabolic diseases were summarized. SAGE Publications 2021-09-23 /pmc/articles/PMC8474302/ /pubmed/34589139 http://dx.doi.org/10.1177/17562848211047130 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Prospects and Challenges into the Role of Gut Microbiome in Health and Disease
Zhang, Lin
Zhan, Hui
Xu, Wenye
Yan, Shuai
Ng, Siew C.
The role of gut mycobiome in health and diseases
title The role of gut mycobiome in health and diseases
title_full The role of gut mycobiome in health and diseases
title_fullStr The role of gut mycobiome in health and diseases
title_full_unstemmed The role of gut mycobiome in health and diseases
title_short The role of gut mycobiome in health and diseases
title_sort role of gut mycobiome in health and diseases
topic Prospects and Challenges into the Role of Gut Microbiome in Health and Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474302/
https://www.ncbi.nlm.nih.gov/pubmed/34589139
http://dx.doi.org/10.1177/17562848211047130
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