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Circulating Tumor DNA as a Biomarker of Radiographic Tumor Burden in SCLC
INTRODUCTION: Blood-based next-generation sequencing assays of circulating tumor DNA (ctDNA) have the ability to detect tumor-associated mutations in patients with SCLC. We sought to characterize the relationship between ctDNA mean variant allele frequency (VAF) and radiographic total-body tumor vol...
Autores principales: | Smith, Jarrod T., Balar, Aneri, Lakhani, Dhairya A., Kluwe, Christien, Zhao, Zhiguo, Kopparapu, Prasad, Almodovar, Karinna, Muterspaugh, Anel, Yan, Yingjun, York, Sally, Horn, Leora, Antic, Sanja, Bertucci, Caterina, Shaffer, Tristan, Hodsdon, Lauren, Garg, Kavita, Hosseini, Seyed Ali, Lim, Lee, Osmundson, Evan, Massion, Pierre P., Lovly, Christine M., Iams, Wade |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474385/ https://www.ncbi.nlm.nih.gov/pubmed/34589992 http://dx.doi.org/10.1016/j.jtocrr.2020.100110 |
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