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Deletion of indoleamine 2,3 dioxygenase (Ido)1 but not Ido2 exacerbates disease symptoms of MOG(35-55)-induced experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) with pathological features of inflammation, demyelination, and neurodegeneration. Several lines of evidence suggest that the enzymes indoleamine 2,3-dioxygenase (Ido)1 and/or Ido2 influences susceptibility to autoim...

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Detalles Bibliográficos
Autores principales:	Wetzel, Lisa A., Hurtado, Myrna, MacDowell Kaswan, Zoe A., McCusker, Robert H., Steelman, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474387/ https://www.ncbi.nlm.nih.gov/pubmed/34589873 http://dx.doi.org/10.1016/j.bbih.2020.100116

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