The protective effect of the TSPO ligands 2,4-Di-Cl-MGV-1, CB86, and CB204 against LPS-induced M1 pro-inflammatory activation of microglia

We have shown previously, that the 18 ​kDa translocator protein (TSPO) synthetic ligands quinazoline derivatives (2-Cl-MGV-1 and MGV-1) can inhibit activation of in BV-2 microglial cells. In the present study we assessed the impact of novel TSPO ligands on lipopolysaccharide (LPS)-induced microglial...

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Detalles Bibliográficos
Autores principales: Monga, Sheelu, Denora, Nunzio, Laquintana, Valentino, Franco, Massimo, Marek, Ilan, Singh, Sukhdev, Nagler, Rafi, Weizman, Abraham, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474401/
https://www.ncbi.nlm.nih.gov/pubmed/34589858
http://dx.doi.org/10.1016/j.bbih.2020.100083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474401/
https://www.ncbi.nlm.nih.gov/pubmed/34589858
http://dx.doi.org/10.1016/j.bbih.2020.100083

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