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The protective effect of the TSPO ligands 2,4-Di-Cl-MGV-1, CB86, and CB204 against LPS-induced M1 pro-inflammatory activation of microglia
We have shown previously, that the 18 kDa translocator protein (TSPO) synthetic ligands quinazoline derivatives (2-Cl-MGV-1 and MGV-1) can inhibit activation of in BV-2 microglial cells. In the present study we assessed the impact of novel TSPO ligands on lipopolysaccharide (LPS)-induced microglial...
Autores principales: | Monga, Sheelu, Denora, Nunzio, Laquintana, Valentino, Franco, Massimo, Marek, Ilan, Singh, Sukhdev, Nagler, Rafi, Weizman, Abraham, Gavish, Moshe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474401/ https://www.ncbi.nlm.nih.gov/pubmed/34589858 http://dx.doi.org/10.1016/j.bbih.2020.100083 |
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