Cargando…

A pilot [(11)C]PBR28 PET/MRI study of neuroinflammation and neurodegeneration in chronic stroke patients

Neuroinflammation occurs in response to acute ischemic stroke, and has been speculated to underlie secondary poststroke pathologies, such as depression, that often develop over time poststroke. However, no study has examined whether neuroinflammation is present in chronic stroke patients (e.g., ≥ ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schaechter, Judith D., Hightower, Baileigh G., Kim, Minhae, Loggia, Marco L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474408/ https://www.ncbi.nlm.nih.gov/pubmed/34589819 http://dx.doi.org/10.1016/j.bbih.2021.100336

Ejemplares similares

Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [(11)C]PBR28 PET correlates with vascular disease measures
por: VanElzakker, Michael B., et al.
Publicado: (2023)

Neuroinflammation in frontotemporal lobar degeneration revealed by (11)C‐PBR28 PET
por: Kim, Min-Jeong, et al.
Publicado: (2019)

Association of neuroinflammation with episodic memory: a [(11)C]PBR28 PET study in cognitively discordant twin pairs
por: Lindgren, Noora, et al.
Publicado: (2020)

Parametric mapping using spectral analysis for (11)C-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects
por: Fan, Zhen, et al.
Publicado: (2018)

The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [(11)C]PBR28 binding and exploration of its link to post-operative delirium
por: Katsumi, Yuta, et al.
Publicado: (2020)

The pandemic brain: Neuroinflammation in non-infected individuals during the COVID-19 pandemic
por: Brusaferri, Ludovica, et al.
Publicado: (2022)

Improved Automated Radiosynthesis of [(11)C]PBR28
por: Solingapuram Sai, Kiran Kumar, et al.
Publicado: (2015)

[(11)C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder
por: Zürcher, N. R., et al.
Publicado: (2020)

Integrated imaging of [(11)C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy (1)H-MRS in amyotrophic lateral sclerosis
por: Ratai, Eva-Maria, et al.
Publicado: (2018)

Assessment of simplified ratio-based approaches for quantification of PET [(11)C]PBR28 data
por: Matheson, Granville J., et al.
Publicado: (2017)

Microglial depletion and activation: A [(11)C]PBR28 PET study in nonhuman primates
por: Hillmer, Ansel T., et al.
Publicado: (2017)

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [(11)C]-PBR28
por: Zürcher, Nicole R., et al.
Publicado: (2015)

A dual tracer [(11)C]PBR28 and [(18)F]FDG microPET evaluation of neuroinflammation and brain energy metabolism in murine endotoxemia
por: Palandira, Santhoshi P., et al.
Publicado: (2022)

Neuroinflammation in World Trade Center responders at midlife: A pilot study using [(18)F]-FEPPA PET imaging
por: Deri, Yael, et al.
Publicado: (2021)

Association of Early β-Amyloid Accumulation and Neuroinflammation Measured With [(11)C]PBR28 in Elderly Individuals Without Dementia
por: Toppala, Sini, et al.
Publicado: (2021)

Positron Emission Tomography studies with [(11)C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation
por: Tóth, Miklós, et al.
Publicado: (2015)

Influence of alcoholism and cholesterol on TSPO binding in brain: PET [(11)C]PBR28 studies in humans and rodents
por: Kim, Sung Won, et al.
Publicado: (2018)

[(11)C]Methionine and [(11)C]PBR28 as PET Imaging Tracers to Differentiate Metastatic Tumor Recurrence or Radiation Necrosis
por: Tran, Thuy T., et al.
Publicado: (2020)

Utility of (18) F-FDG and (11)C-PBR28 microPET for the assessment of rat aortic aneurysm inflammation
por: English, Sean J, et al.
Publicado: (2014)

Quantification of [(11)C]PBR28 data after systemic lipopolysaccharide challenge
por: Woodcock, Eric A., et al.
Publicado: (2020)

Evaluating [(11)C]PBR28 PET for Monitoring Gut and Brain Inflammation in a Rat Model of Chemically Induced Colitis
por: Kurtys, E., et al.
Publicado: (2016)

Image-Derived Input Function for Human Brain Using High Resolution PET Imaging with [(11)C](R)-rolipram and [(11)C]PBR28
por: Zanotti-Fregonara, Paolo, et al.
Publicado: (2011)

Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [(11)C]PBR28 HRRT PET study
por: Tuisku, Jouni, et al.
Publicado: (2019)

Decreased hippocampal translocator protein (18 kDa) expression in alcohol dependence: a [(11)C]PBR28 PET study
por: Kalk, N J, et al.
Publicado: (2017)

The Lentiviral Vector Pseudotyped by Modified Rabies Glycoprotein Does Not Cause Reactive Gliosis and Neurodegeneration in Rat Hippocampus
por: Farzaneh, Mostafa, et al.
Publicado: (2019)

PET imaging of [(11)C]PBR28 in Parkinson’s disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding
por: Varnäs, Katarina, et al.
Publicado: (2018)

Mapping the interaction between Trim28 and the KRAB domain at the center of Trim28 silencing of endogenous retroviruses
por: Taka, Jamie R. H., et al.
Publicado: (2022)

An In Vivo Study of a Rat Fluid-Percussion-Induced Traumatic Brain Injury Model with [(11)C]PBR28 and [(18)F]flumazenil PET Imaging
por: Ghosh, Krishna Kanta, et al.
Publicado: (2021)

Estimation of blood-based biomarkers of glial activation related to neuroinflammation
por: Yasuno, Fumihiko, et al.
Publicado: (2022)

An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28
por: Owen, David R, et al.
Publicado: (2012)

Direct Comparison of [(18)F]F-DPA with [(18)F]DPA-714 and [(11)C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls
por: López-Picón, Francisco R., et al.
Publicado: (2021)

Test-retest analysis of a non-invasive method of quantifying [(11)C]-PBR28 binding in Alzheimer’s disease
por: Nair, Akshay, et al.
Publicado: (2016)

Investigation of the halophilic PET hydrolase PET6 from Vibrio gazogenes
por: Weigert, Sebastian, et al.
Publicado: (2022)

Moderate noise associated oxidative stress with concomitant memory impairment, neuro-inflammation and neurodegeneration
por: Shukla, Manish, et al.
Publicado: (2020)

Early-life inflammatory markers and subsequent psychotic and depressive episodes between 10 to 28 years of age
por: Edmondson-Stait, Amelia J., et al.
Publicado: (2022)

Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration
por: Garza, Alejandra P., et al.
Publicado: (2023)

Evaluation of exercise-induced modulation of glial activation and dopaminergic damage in a rat model of Parkinson’s disease using [(11)C]PBR28 and [(18)F]FDOPA PET
por: Real, Caroline C, et al.
Publicado: (2017)

Erratum to: Test-retest analysis of a non-invasive method of quantifying [(11)C]-PBR28 binding in Alzheimer's disease
por: Nair, Akshay, et al.
Publicado: (2017)

Specific and non-specific binding of a tracer for the translocator-specific protein in schizophrenia: an [11C]-PBR28 blocking study
por: Marques, Tiago Reis, et al.
Publicado: (2021)

pKr-2 induces neurodegeneration via upregulation of microglial TLR4 in the hippocampus of AD brain
por: Kim, Sehwan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ceqhbegd3dmuvni28istjae7bq