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Subacute metformin treatment reduces inflammation and improves functional outcome following neonatal hypoxia ischemia
Hypoxia-ischemia (HI) injury is a leading cause of neonatal death and long-term disability, and existing treatment options for HI offer only modest benefit. Early intervention with the drug metformin has been shown to promote functional improvement in numerous rodent models of injury and has pleiotr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474427/ https://www.ncbi.nlm.nih.gov/pubmed/34589876 http://dx.doi.org/10.1016/j.bbih.2020.100119 |