An enriched environment prevents cognitive impairment in an Alzheimer’s disease model by enhancing the secretion of exosomal microRNA-146a from the choroid plexus

Alzheimer’s disease (AD) is characterized by the extensive deposition of amyloid-β plaques and neurofibrillary tangles. We previously found that preserved function of astrocytes is associated with cognitively normal subjects with AD pathology. Here we show that an enriched environment (EE) can preve...

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Detalles Bibliográficos
Autores principales: Nakano, Masako, Kubota, Kenta, Hashizume, Shin, Kobayashi, Eiji, Chikenji, Takako S., Saito, Yuki, Fujimiya, Mineko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474441/
https://www.ncbi.nlm.nih.gov/pubmed/34589894
http://dx.doi.org/10.1016/j.bbih.2020.100149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474441/
https://www.ncbi.nlm.nih.gov/pubmed/34589894
http://dx.doi.org/10.1016/j.bbih.2020.100149

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