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Depression and anxiety in patients with multiple sclerosis treated with interferon-beta or fingolimod: Role of indoleamine 2,3-dioxygenase and pro-inflammatory cytokines
Depression/anxiety (D/A) occurs in up to 50% of multiple sclerosis (MS) patients. Proinflammatory cytokines induce classical symptoms of depression. Activation of the inflammatory response also triggers production of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, the amino acid pre...
Autores principales: | Tauil, Carlos B., da Rocha Lima, Amanda D., Ferrari, Breno B., da Silva, Verônica A.G., Moraes, Adriel S., da Silva, Flávia M., Melo-Silva, César A., Farias, Alessandro S., Brandão, Carlos O., Leonilda, M.B. dosSantos, dos Santos-Neto, Leopoldo L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474597/ https://www.ncbi.nlm.nih.gov/pubmed/34589900 http://dx.doi.org/10.1016/j.bbih.2020.100162 |
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