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Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier

The proinflammatory cytokine Interleukin-1 (IL-1), with its two isoforms α and β, has important roles in multiple pathogenic processes in the central nervous system. The present study aimed to evaluate and compare the blood-to-brain distribution of anakinra (IL-1 receptor antagonist), bermekimab (IL...

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Detalles Bibliográficos
Autores principales:	Sjöström, Elisabet O., Culot, Maxime, Leickt, Lisa, Åstrand, Mikael, Nordling, Erik, Gosselet, Fabien, Kaiser, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474601/ https://www.ncbi.nlm.nih.gov/pubmed/34589799 http://dx.doi.org/10.1016/j.bbih.2021.100307

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