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Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid

INTRODUCTION: Amitriptyline is prescribed to reduce the intensity of chronic neuropathic pain. There is a paucity of validated in vivo evidence in humans regarding amitriptyline’s mechanism of action. We examined the effect of amitriptyline therapy on cerebrospinal fluid (CSF) neuropeptides and prot...

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Detalles Bibliográficos
Autores principales:	Royds, Jonathan, Cassidy, Hilary, Conroy, Melissa J., Dunne, Margaret R., Lysaght, Joanne, McCrory, Connail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474617/ https://www.ncbi.nlm.nih.gov/pubmed/34589721 http://dx.doi.org/10.1016/j.bbih.2020.100184

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