Cargando…
Developmental ablation of mature oligodendrocytes exacerbates adult CNS demyelination
Multiple sclerosis (MS) is a CNS neurodegenerative autoimmune disease characterized by loss of oligodendrocytes and myelin in the brain and the spinal cord that results in localized functional deficits. Several risk factors have been associated with MS, however none fully explain the enhanced suscep...
Autores principales: | Pajoohesh-Ganji, Ahdeah, Karl, Molly, Garrison, Eric, Osei-Bonsu, Nana Adwoa, Clarkson-Paredes, Cheryl, Ahn, Julie, Miller, Robert H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474627/ https://www.ncbi.nlm.nih.gov/pubmed/34589870 http://dx.doi.org/10.1016/j.bbih.2020.100110 |
Ejemplares similares
-
Oligodendrocyte ablation as a tool to study demyelinating diseases
por: Pajoohesh-Ganji, Ahdeah, et al.
Publicado: (2016) -
Targeted Oligodendrocyte Apoptosis in Optic Nerve Leads to Persistent Demyelination
por: Pajoohesh-Ganji, Ahdeah, et al.
Publicado: (2019) -
K14 + Compound niches are present on the mouse cornea early after birth and expand after debridement wounds
por: Pajoohesh‐Ganji, Ahdeah, et al.
Publicado: (2015) -
Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion
por: Wu, Junfang, et al.
Publicado: (2012) -
Semaphorin4A causes loss of mature oligodendrocytes and demyelination in vivo
por: Chiou, Brian, et al.
Publicado: (2019)