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Accelerated hematopoietic mitotic aging measured by DNA methylation, blood cell lineage, and Parkinson’s disease

BACKGROUND: Aging and inflammation are important components of Parkinson’s disease (PD) pathogenesis and both are associated with changes in hematopoiesis and blood cell composition. DNA methylation (DNAm) presents a mechanism to investigate inflammation, aging, and hematopoiesis in PD, using epigen...

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Detalles Bibliográficos
Autores principales:	Paul, Kimberly C, Binder, Alexandra M, Horvath, Steve, Kusters, Cynthia, Yan, Qi, Rosario, Irish Del, Yu, Yu, Bronstein, Jeff, Ritz, Beate
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474781/ https://www.ncbi.nlm.nih.gov/pubmed/34565328 http://dx.doi.org/10.1186/s12864-021-08009-y

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