Effect of low-dose amitriptyline on reducing pain in clinical knee osteoarthritis compared to benztropine: study protocol of a randomised, double blind, placebo-controlled trial

BACKGROUND: Knee osteoarthritis is a major cause of pain and disability. Pain control is poor, with most patients remaining in moderate to severe pain. This may be because central causes of pain, a common contributor to knee pain, are not affected by current treatment strategies. Antidepressants, su...

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Detalles Bibliográficos
Autores principales: Wluka, Anita E., Urquhart, Donna M., Teichtahl, Andrew J., Hussain, Sultana Monira, Forbes, Andrew, Arnold, Carolyn, Wang, Yuanyuan, Cicuttini, Flavia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474789/
https://www.ncbi.nlm.nih.gov/pubmed/34579675
http://dx.doi.org/10.1186/s12891-021-04690-y

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