miR‐133a Replacement Attenuates Thoracic Aortic Aneurysm in Mice

BACKGROUND: Thoracic aortic aneurysms (TAAs) occur because of abnormal remodeling of aortic extracellular matrix and are accompanied by the emergence of proteolytically active myofibroblasts. The microRNA miR‐133a regulates cellular phenotypes and is reduced in clinical TAA specimens. This study tes...

Descripción completa

Detalles Bibliográficos
Autores principales: Akerman, Adam W., Collins, Elizabeth N., Peterson, Andrew R., Collins, Lauren B., Harrison, Jessica K., DeVaughn, Amari, Townsend, Jaleel M., Vanbuskirk, Rebecca L., Riopedre‐Maqueira, Jessica, Reyes, Ailet, Oh, Joyce E., Raybuck, Charles M., Jones, Jeffrey A., Ikonomidis, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475064/
https://www.ncbi.nlm.nih.gov/pubmed/34387094
http://dx.doi.org/10.1161/JAHA.120.019862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475064/
https://www.ncbi.nlm.nih.gov/pubmed/34387094
http://dx.doi.org/10.1161/JAHA.120.019862

Ejemplares similares