Identification of a Proline-Kinked Amphipathic α-Helix Downstream from the Methyltransferase Domain of a Potexvirus Replicase and Its Role in Virus Replication and Perinuclear Complex Formation

Characterized positive-strand RNA viruses replicate in association with intracellular membranes. Regarding viruses in the genus Potexvirus, the mechanism by which their RNA-dependent RNA polymerase (replicase) associates with membranes is understudied. Here, by membrane flotation analyses of the rep...

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Detalles Bibliográficos
Autores principales: Komatsu, Ken, Sasaki, Nobumitsu, Yoshida, Tetsuya, Suzuki, Katsuhiro, Masujima, Yuki, Hashimoto, Masayoshi, Watanabe, Satoru, Tochio, Naoya, Kigawa, Takanori, Yamaji, Yasuyuki, Oshima, Kenro, Namba, Shigetou, Nelson, Richard S., Arie, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475525/
https://www.ncbi.nlm.nih.gov/pubmed/34346768
http://dx.doi.org/10.1128/JVI.01906-20

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