Cargando…

Genetically Predicted Insomnia in Relation to 14 Cardiovascular Conditions and 17 Cardiometabolic Risk Factors: A Mendelian Randomization Study

BACKGROUND: This Mendelian randomization study aims to investigate causal associations between genetically predicted insomnia and 14 cardiovascular diseases (CVDs) as well as the potential mediator role of 17 cardiometabolic risk factors. METHODS AND RESULTS: Using genetic association estimates from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xinhui, Li, Chuanbao, Sun, Xiaoru, Yu, Yuanyuan, Si, Shucheng, Hou, Lei, Yan, Ran, Yu, Yifan, Li, Mingzhuo, Li, Hongkai, Xue, Fuzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475657/ https://www.ncbi.nlm.nih.gov/pubmed/34315237 http://dx.doi.org/10.1161/JAHA.120.020187

Ejemplares similares

Impact of nonrandom selection mechanisms on the causal effect estimation for two-sample Mendelian randomization methods
por: Yu, Yuanyuan, et al.
Publicado: (2022)

Lipids, Anthropometric Measures, Smoking and Physical Activity Mediate the Causal Pathway From Education to Breast Cancer in Women: A Mendelian Randomization Study
por: Li, Hongkai, et al.
Publicado: (2021)

Exploring the causal pathway from ischemic stroke to atrial fibrillation: a network Mendelian randomization study
por: Hou, Lei, et al.
Publicado: (2020)

Exploring the Causal Roles of Circulating Remnant Lipid Profile on Cardiovascular and Cerebrovascular Diseases: Mendelian Randomization Study
por: Si, Shucheng, et al.
Publicado: (2022)

Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma
por: Sun, Xiaoru, et al.
Publicado: (2021)

Association between dietary habits and the risk of migraine: a Mendelian randomization study
por: Liu, Xinhui, et al.
Publicado: (2023)

Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions
por: Liu, Xinhui, et al.
Publicado: (2022)

Causal associations between female reproductive behaviors and psychiatric disorders: a lifecourse Mendelian randomization study
por: Yu, Yifan, et al.
Publicado: (2023)

Causal Effect of the Triglyceride-Glucose Index and the Joint Exposure of Higher Glucose and Triglyceride With Extensive Cardio-Cerebrovascular Metabolic Outcomes in the UK Biobank: A Mendelian Randomization Study
por: Si, Shucheng, et al.
Publicado: (2021)

A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology
por: Li, Hongkai, et al.
Publicado: (2020)

A novel method for controlling unobserved confounding using double confounders
por: Liu, Lu, et al.
Publicado: (2020)

Genetically Determined Chronic Low-Grade Inflammation and Hundreds of Health Outcomes in the UK Biobank and the FinnGen Population: A Phenome-Wide Mendelian Randomization Study
por: Si, Shucheng, et al.
Publicado: (2021)

A simulation study on matched case-control designs in the perspective of causal diagrams
por: Li, Hongkai, et al.
Publicado: (2016)

Roles for circulating polyunsaturated fatty acids in ischemic stroke and modifiable factors: a Mendelian randomization study
por: Yuan, Tonghui, et al.
Publicado: (2020)

Acute coronary syndrome screening in patients presenting with arteriosclerosis in health check-ups: a case–control study
por: Li, Xiaoxing, et al.
Publicado: (2022)

Sensitivity analysis for mistakenly adjusting for mediators in estimating total effect in observational studies
por: Wang, Tingting, et al.
Publicado: (2017)

Leisure-Time Physical Activity and Cardiovascular Disease Risk Among Hypertensive Patients: A Longitudinal Cohort Study
por: Li, Jiqing, et al.
Publicado: (2021)

The alarming problems of confounding equivalence using logistic regression models in the perspective of causal diagrams
por: Yu, Yuanyuan, et al.
Publicado: (2017)

Genetic liability to insomnia in relation to cardiovascular diseases: a Mendelian randomisation study
por: Yuan, Shuai, et al.
Publicado: (2021)

Association between insomnia and COVID-19: A Bi-directional mendelian randomization analysis
por: Ran, Shu, et al.
Publicado: (2023)

Association between antipsychotic agents and risk of lung cancer: a nested case‐control study
por: Li, Jiqing, et al.
Publicado: (2022)

SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study
por: Xu, Min, et al.
Publicado: (2022)

Schizophrenia and cardiometabolic abnormalities: A Mendelian randomization study
por: Saadullah Khani, Noushin, et al.
Publicado: (2023)

Effects of Insomnia on Peptic Ulcer Disease Using Mendelian Randomization
por: Zha, Ling-Feng, et al.
Publicado: (2021)

Genetic Liability to Insomnia and Lung Cancer Risk: A Mendelian Randomization Analysis
por: Shen, Jiayi, et al.
Publicado: (2021)

Insomnia and circadian misalignment: an underexplored interaction towards cardiometabolic risk
por: Nobre, Barbara, et al.
Publicado: (2021)

Alleviating insomnia should decrease the risk of irritable bowel syndrome: Evidence from Mendelian randomization
por: Bao, Wenzhao, et al.
Publicado: (2022)

Causal relationship between insomnia and tuberculosis: A bi-directional Mendelian randomization analysis
por: Zhang, Shaobin, et al.
Publicado: (2022)

Exploring genetic association of insomnia with allergic disease and asthma: a bidirectional Mendelian randomization study
por: Li, Rong, et al.
Publicado: (2022)

Mendelian randomization highlights insomnia as a risk factor for pain diagnoses
por: Broberg, Martin, et al.
Publicado: (2021)

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
por: Fall, Tove, et al.
Publicado: (2013)

IGF-1 and cardiometabolic diseases: a Mendelian randomisation study
por: Larsson, Susanna C., et al.
Publicado: (2020)

Network Mendelian randomization study: exploring the causal pathway from insomnia to type 2 diabetes
por: Xiuyun, Wen, et al.
Publicado: (2022)

Comparative efficacy and safety of glucose-lowering drugs in children and adolescents with type 2 diabetes: A systematic review and network meta-analysis
por: Wu, Sijia, et al.
Publicado: (2022)

Assessment of causal direction between thyroid function and cardiometabolic health: a Mendelian randomization study
por: WANG, Jing-Jia, et al.
Publicado: (2022)

Effects of antipsychotics on triglyceride trajectories and its implications in CVD: A longitudinal cohort study
por: Li, Jiqing, et al.
Publicado: (2022)

Association of Genetically Predicted Insomnia With Risk of Sepsis: A Mendelian Randomization Study
por: Thorkildsen, Marianne S., et al.
Publicado: (2023)

Blood copper and risk of cardiometabolic diseases: a Mendelian randomization study
por: Jäger, Susanne, et al.
Publicado: (2021)

A Reappraisal on the Associations between Sleep-disordered Breathing, Insomnia, and Cardiometabolic Risk
por: Meira e Cruz, Miguel, et al.
Publicado: (2021)

The Causal Effects of Insomnia on Bipolar Disorder, Depression, and Schizophrenia: A Two-Sample Mendelian Randomization Study
por: Huang, Peng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ik3ct4m2100gcdq53f0cknan7n