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Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device

Left ventricular assist devices (LVAD) are increasingly being used as destination therapy in patients with Stage D heart failure. It has been reported that a majority of patients who receive a durable LVAD (dLVAD) present in cardiogenic shock due to decompensated heart failure (ADHF‐CS). As it stand...

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Autores principales: Brown, Matthew A., Sheikh, Farooq H., Ahmed, Sara, Najjar, Samer S., Molina, Ezequiel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475697/
https://www.ncbi.nlm.nih.gov/pubmed/34308683
http://dx.doi.org/10.1161/JAHA.120.019376
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author Brown, Matthew A.
Sheikh, Farooq H.
Ahmed, Sara
Najjar, Samer S.
Molina, Ezequiel J.
author_facet Brown, Matthew A.
Sheikh, Farooq H.
Ahmed, Sara
Najjar, Samer S.
Molina, Ezequiel J.
author_sort Brown, Matthew A.
collection PubMed
description Left ventricular assist devices (LVAD) are increasingly being used as destination therapy in patients with Stage D heart failure. It has been reported that a majority of patients who receive a durable LVAD (dLVAD) present in cardiogenic shock due to decompensated heart failure (ADHF‐CS). As it stands, there is no consensus on the optimal management strategy for patients presenting with ADHF. Bridging with intra‐aortic balloon pumps (IABPs) continues to be a therapeutic option in patients with hemodynamic instability due to cardiogenic shock. The majority of data regarding the use of IABP in cardiogenic shock come from studies in patients presenting with acute myocardial infarction with cardiogenic shock and demonstrates that there is no benefit of routine IABP use in this patient population. However, the role of IABPs as a bridge to dLVAD in ADHF‐CS has yet to be determined. The hemodynamic changes seen in acute myocardial infarction with cardiogenic shock are known to be different and more acutely impaired than those presenting with ADHF‐CS as evidenced by differences in pressure/volume loops. Thus, data should not be extrapolated across these 2 very different disease processes. The aim of this review is to describe results from contemporary studies examining the use of IABPs as a bridge to dLVAD in patients with ADHF‐CS. Retrospective evidence from large registries suggests that the use of IABP as a bridge to dLVAD is feasible and safe when compared with other platforms of temporary mechanical circulatory support. However, there is currently a paucity of high‐quality evidence examining this increasingly important clinical question.
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spelling pubmed-84756972021-10-01 Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device Brown, Matthew A. Sheikh, Farooq H. Ahmed, Sara Najjar, Samer S. Molina, Ezequiel J. J Am Heart Assoc Contemporary Review Left ventricular assist devices (LVAD) are increasingly being used as destination therapy in patients with Stage D heart failure. It has been reported that a majority of patients who receive a durable LVAD (dLVAD) present in cardiogenic shock due to decompensated heart failure (ADHF‐CS). As it stands, there is no consensus on the optimal management strategy for patients presenting with ADHF. Bridging with intra‐aortic balloon pumps (IABPs) continues to be a therapeutic option in patients with hemodynamic instability due to cardiogenic shock. The majority of data regarding the use of IABP in cardiogenic shock come from studies in patients presenting with acute myocardial infarction with cardiogenic shock and demonstrates that there is no benefit of routine IABP use in this patient population. However, the role of IABPs as a bridge to dLVAD in ADHF‐CS has yet to be determined. The hemodynamic changes seen in acute myocardial infarction with cardiogenic shock are known to be different and more acutely impaired than those presenting with ADHF‐CS as evidenced by differences in pressure/volume loops. Thus, data should not be extrapolated across these 2 very different disease processes. The aim of this review is to describe results from contemporary studies examining the use of IABPs as a bridge to dLVAD in patients with ADHF‐CS. Retrospective evidence from large registries suggests that the use of IABP as a bridge to dLVAD is feasible and safe when compared with other platforms of temporary mechanical circulatory support. However, there is currently a paucity of high‐quality evidence examining this increasingly important clinical question. John Wiley and Sons Inc. 2021-07-26 /pmc/articles/PMC8475697/ /pubmed/34308683 http://dx.doi.org/10.1161/JAHA.120.019376 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Contemporary Review
Brown, Matthew A.
Sheikh, Farooq H.
Ahmed, Sara
Najjar, Samer S.
Molina, Ezequiel J.
Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device
title Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device
title_full Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device
title_fullStr Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device
title_full_unstemmed Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device
title_short Intra‐Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device
title_sort intra‐aortic balloon pump as a bridge to durable left ventricular assist device
topic Contemporary Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475697/
https://www.ncbi.nlm.nih.gov/pubmed/34308683
http://dx.doi.org/10.1161/JAHA.120.019376
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