Pre-existing Autoantibodies Neutralizing High Concentrations of Type I Interferons in Almost 10% of COVID-19 Patients Admitted to Intensive Care in Barcelona

BACKGROUND: It is important to predict which patients infected by SARS-CoV-2 are at higher risk of life-threatening COVID-19. Several studies suggest that neutralizing auto-antibodies (auto-Abs) against type I interferons (IFNs) are predictive of critical COVID-19 pneumonia. OBJECTIVES: We aimed to...

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Detalles Bibliográficos
Autores principales: Solanich, Xavier, Rigo-Bonnin, Raúl, Gumucio, Victor-David, Bastard, Paul, Rosain, Jérémie, Philippot, Quentin, Perez-Fernandez, Xosé-Luis, Fuset-Cabanes, Maria-Paz, Gordillo-Benitez, Miguel-Ángel, Suarez-Cuartin, Guillermo, Boza-Hernandez, Enric, Riera-Mestre, Antoni, Parra-Martínez, Alba, Colobran, Roger, Antolí, Arnau, Navarro, Sergio, Rocamora-Blanch, Gemma, Framil, Mario, Calatayud, Laura, Corbella, Xavier, Casanova, Jean-Laurent, Morandeira, Francisco, Sabater-Riera, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475877/
https://www.ncbi.nlm.nih.gov/pubmed/34570326
http://dx.doi.org/10.1007/s10875-021-01136-x

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