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Probing T-cell response by sequence-based probabilistic modeling

With the increasing ability to use high-throughput next-generation sequencing to quantify the diversity of the human T cell receptor (TCR) repertoire, the ability to use TCR sequences to infer antigen-specificity could greatly aid potential diagnostics and therapeutics. Here, we use a machine-learni...

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Detalles Bibliográficos
Autores principales: Bravi, Barbara, Balachandran, Vinod P., Greenbaum, Benjamin D., Walczak, Aleksandra M., Mora, Thierry, Monasson, Rémi, Cocco, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476001/
https://www.ncbi.nlm.nih.gov/pubmed/34473697
http://dx.doi.org/10.1371/journal.pcbi.1009297

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