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Bergamottin a CYP3A inhibitor found in grapefruit juice inhibits prostate cancer cell growth by downregulating androgen receptor signaling and promoting G0/G1 cell cycle block and apoptosis

Prostate cancer is the second leading cause of cancer related death in American men. Several therapies have been developed to treat advanced prostate cancer, but these therapies often have severe side effects. To improve the outcome with fewer side effects we focused on the furanocoumarin bergamotti...

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Detalles Bibliográficos
Autores principales:	Vetrichelvan, Opalina, Gorjala, Priyatham, Goodman, Oscar, Mitra, Ranjana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476002/ https://www.ncbi.nlm.nih.gov/pubmed/34570813 http://dx.doi.org/10.1371/journal.pone.0257984

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