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FunOrder: A robust and semi-automated method for the identification of essential biosynthetic genes through computational molecular co-evolution

Secondary metabolites (SMs) are a vast group of compounds with different structures and properties that have been utilized as drugs, food additives, dyes, and as monomers for novel plastics. In many cases, the biosynthesis of SMs is catalysed by enzymes whose corresponding genes are co-localized in...

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Detalles Bibliográficos
Autores principales: Vignolle, Gabriel A., Schaffer, Denise, Zehetner, Leopold, Mach, Robert L., Mach-Aigner, Astrid R., Derntl, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476034/
https://www.ncbi.nlm.nih.gov/pubmed/34570757
http://dx.doi.org/10.1371/journal.pcbi.1009372