Cargando…

Identification and validation of circulating miRNAs as potential new biomarkers for severe liver disease in patients with leptospirosis

BACKGROUND: Leptospirosis, a global zoonotic infectious disease, has various clinical manifestations ranging from mild self-limiting illness to life-threatening with multi-organ damage, including liver involvement. This study was aimed at identifying circulating microRNAs (miRNAs) as novel biomarker...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chuaypen, Natthaya, Limothai, Umaporn, Kunadirek, Pattapon, Kaewsapsak, Pornchai, Kueanjinda, Patipark, Srisawat, Nattachai, Tangkijvanich, Pisit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476044/ https://www.ncbi.nlm.nih.gov/pubmed/34570814 http://dx.doi.org/10.1371/journal.pone.0257805

Ejemplares similares

Circulating microtranscriptome profiles reveal distinct expression of microRNAs in severe leptospirosis
por: Limothai, Umaporn, et al.
Publicado: (2020)

Transcriptomic Analyses Reveal Long Non-Coding RNA in Peripheral Blood Mononuclear Cells as a Novel Biomarker for Diagnosis and Prognosis of Hepatocellular Carcinoma
por: Kunadirek, Pattapon, et al.
Publicado: (2022)

The expression of FLNA and CLU in PBMCs as a novel screening marker for hepatocellular carcinoma
por: Patarat, Rathasapa, et al.
Publicado: (2021)

Cell-Free DNA Analysis by Whole-Exome Sequencing for Hepatocellular Carcinoma: A Pilot Study in Thailand
por: Kunadirek, Pattapon, et al.
Publicado: (2021)

Identification of BHLHE40 expression in peripheral blood mononuclear cells as a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma
por: Kunadirek, Pattapon, et al.
Publicado: (2021)

Discovery and validation of circulating miRNAs for the clinical prognosis of severe dengue
por: Limothai, Umaporn, et al.
Publicado: (2022)

Diagnostic and prognostic roles of circulating miRNA-223-3p in hepatitis B virus–related hepatocellular carcinoma
por: Pratedrat, Pornpitra, et al.
Publicado: (2020)

Circulating Extracellular Vesicle-Derived microRNAs as Novel Diagnostic and Prognostic Biomarkers for Non-Viral-Related Hepatocellular Carcinoma
por: Boonkaew, Bootsakorn, et al.
Publicado: (2023)

Predictive Role of Pretreatment Circulating miR-221 in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization
por: Pinjaroen, Nutcha, et al.
Publicado: (2023)

The combination of RPA-CRISPR/Cas12a and Leptospira IgM RDT enhances the early detection of leptospirosis
por: Jirawannaporn, Sirawit, et al.
Publicado: (2023)

MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury
por: Ariyachet, Chaiyaboot, et al.
Publicado: (2022)

A prospective study to evaluate the accuracy of rapid diagnostic tests for diagnosis of human leptospirosis: Result from THAI-LEPTO AKI study
por: Dinhuzen, Janejira, et al.
Publicado: (2021)

An innovative wireless electrochemical card sensor for field-deployable diagnostics of Hepatitis B surface antigen
por: Teengam, Prinjaporn, et al.
Publicado: (2023)

Seroprevalence of leptospirosis among blood donors in an endemic area
por: Limothai, Umaporn, et al.
Publicado: (2023)

The role of leptospiremia and specific immune response in severe leptospirosis
por: Limothai, Umaporn, et al.
Publicado: (2021)

Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury
por: Phulkerd, Thanawat, et al.
Publicado: (2022)

The Association of PNPLA3, COX-2 and DHCR7 Polymorphisms with Advanced Liver Fibrosis in Patients with HCV Mono-Infection and HCV/HIV Co-Infection
por: Kiatbumrung, Rattanaporn, et al.
Publicado: (2018)

Association of NTCP polymorphisms with clinical outcome of hepatitis B infection in Thai individuals
por: Chuaypen, Natthaya, et al.
Publicado: (2019)

Successful direct-acting antiviral therapy improves circulating mucosal-associated invariant T cells in patients with chronic HCV infection
por: Khlaiphuengsin, Apichaya, et al.
Publicado: (2020)

Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants
por: Chuaypen, Natthaya, et al.
Publicado: (2022)

Litchi-Derived Polyphenol Alleviates Liver Steatosis and Gut Dysbiosis in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Double-Blinded, Placebo-Controlled Study
por: Jinato, Thananya, et al.
Publicado: (2022)

Long-term benefit of DAAs on gut dysbiosis and microbial translocation in HCV-infected patients with and without HIV coinfection
por: Chuaypen, Natthaya, et al.
Publicado: (2023)

Decreased of BAFF-R expression and B cells maturation in patients with hepatitis B virus-related hepatocellular carcinoma
por: Khlaiphuengsin, Apichaya, et al.
Publicado: (2020)

Prevalence and genotype distribution of hepatitis C virus within hemodialysis units in Thailand: role of HCV core antigen in the assessment of viremia
por: Chuaypen, Natthaya, et al.
Publicado: (2022)

Targeted Proteins Reveal Cathepsin D as a Novel Biomarker in Differentiating Hepatocellular Carcinoma from Cirrhosis and Other Liver Cancers
por: Chuaypen, Natthaya, et al.
Publicado: (2022)

Development and Validation of a simple score for diagnosis of Leptospirosis at outpatient departments
por: Temeiam, Nidhikul, et al.
Publicado: (2020)

Rapid and sensitive point-of-care detection of Leptospira by RPA-CRISPR/Cas12a targeting lipL32
por: Jirawannaporn, Sirawit, et al.
Publicado: (2022)

The Design and Synthesis of a New Series of 1,2,3-Triazole-Cored Structures Tethering Aryl Urea and Their Highly Selective Cytotoxicity toward HepG2
por: Oekchuae, Sittisak, et al.
Publicado: (2022)

Leptospirosis manifested with severe pulmonary haemorrhagic syndrome successfully treated with venovenous extracorporeal membrane oxygenation
por: Chaikajornwat, Jukkaphop, et al.
Publicado: (2020)

Human, animal, water source interactions and leptospirosis in Thailand
por: Narkkul, Udomsak, et al.
Publicado: (2021)

Droplet digital PCR assay provides intrahepatic HBV cccDNA quantification tool for clinical application
por: Hayashi, Sanae, et al.
Publicado: (2022)

Binding characteristics of pyrrole-scaffold hepatitis B virus capsid inhibitors and identification of novel potent compounds
por: Ruengsatra, Tanachote, et al.
Publicado: (2023)

Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures
por: Duttagupta, Radha, et al.
Publicado: (2011)

Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases
por: Katoh, Masaru
Publicado: (2014)

A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4
por: Kueanjinda, Patipark, et al.
Publicado: (2015)

Corrigendum: A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4
por: Kueanjinda, Patipark, et al.
Publicado: (2015)

Notch Signaling in Macrophages in the Context of Cancer Immunity
por: Palaga, Tanapat, et al.
Publicado: (2018)

Circulating miRNAs as Biomarkers for Neurodegenerative Disorders
por: Grasso, Margherita, et al.
Publicado: (2014)

Circulating miRNAs as biomarkers of kidney disease
por: Hüttenhofer, Alexander, et al.
Publicado: (2017)

MiRNAs as Novel Adipokines: Obesity-Related Circulating MiRNAs Influence Chemosensitivity in Cancer Patients
por: Withers, Sarah B., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_24p91aqk7563jle81e4ebkl2vs