IRF4 is Correlated with the Conversion to a Th17-Like Phenotype in Regulatory T Cells from the Malignant Pleural Effusion

BACKGROUND: RORγt(+)Foxp3(+) (Th17-like) Tregs are a plastic Treg subset implicated in immune-related diseases; however, the mechanism of Treg phenotypic transformation in malignant pleural effusion (MPE) has not been elucidated. METHODS: The percentage of CD4(+)CD25(+)Foxp3(+)Helios(+) and RORγt(+)...

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Detalles Bibliográficos
Autores principales: Yu, Wenqing, Ji, Ningfei, Gu, Chengjing, Yao, Juan, Ding, Mingdong, Zhou, Daming, Huang, Mao, Zhang, Mingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476179/
https://www.ncbi.nlm.nih.gov/pubmed/34588805
http://dx.doi.org/10.2147/IJGM.S330389

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