Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome

Chédiak–Higashi syndrome (CHS), a rare autosomal recessive disorder associated with leukocyte dysfunction, is characterised by partial skin and hair albinism, immunodeficiency, and abnormal bleeding. Furthermore, it may be associated with cognitive and neurological impairments. The long-term prognos...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimizu, Kasumi, Hayashi, Miho, Ito, Nozomi, Hamada, Kokoro, Koizumi, Gaku, Kurohara, Kazuto, Arai, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476280/
https://www.ncbi.nlm.nih.gov/pubmed/34589239
http://dx.doi.org/10.1155/2021/9918199
_version_ 1784575575320428544
author Shimizu, Kasumi
Hayashi, Miho
Ito, Nozomi
Hamada, Kokoro
Koizumi, Gaku
Kurohara, Kazuto
Arai, Naoya
author_facet Shimizu, Kasumi
Hayashi, Miho
Ito, Nozomi
Hamada, Kokoro
Koizumi, Gaku
Kurohara, Kazuto
Arai, Naoya
author_sort Shimizu, Kasumi
collection PubMed
description Chédiak–Higashi syndrome (CHS), a rare autosomal recessive disorder associated with leukocyte dysfunction, is characterised by partial skin and hair albinism, immunodeficiency, and abnormal bleeding. Furthermore, it may be associated with cognitive and neurological impairments. The long-term prognosis of patients is generally poor, and haematopoietic stem cell transplantation is a radical immunodeficiency treatment. Here, we report a case of successful oral management of an 18-year-old woman with CHS accompanied by aggressive periodontitis who underwent haematopoietic stem cell transplantation.
format Online
Article
Text
id pubmed-8476280
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-84762802021-09-28 Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome Shimizu, Kasumi Hayashi, Miho Ito, Nozomi Hamada, Kokoro Koizumi, Gaku Kurohara, Kazuto Arai, Naoya Case Rep Dent Case Report Chédiak–Higashi syndrome (CHS), a rare autosomal recessive disorder associated with leukocyte dysfunction, is characterised by partial skin and hair albinism, immunodeficiency, and abnormal bleeding. Furthermore, it may be associated with cognitive and neurological impairments. The long-term prognosis of patients is generally poor, and haematopoietic stem cell transplantation is a radical immunodeficiency treatment. Here, we report a case of successful oral management of an 18-year-old woman with CHS accompanied by aggressive periodontitis who underwent haematopoietic stem cell transplantation. Hindawi 2021-09-20 /pmc/articles/PMC8476280/ /pubmed/34589239 http://dx.doi.org/10.1155/2021/9918199 Text en Copyright © 2021 Kasumi Shimizu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shimizu, Kasumi
Hayashi, Miho
Ito, Nozomi
Hamada, Kokoro
Koizumi, Gaku
Kurohara, Kazuto
Arai, Naoya
Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome
title Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome
title_full Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome
title_fullStr Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome
title_full_unstemmed Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome
title_short Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak–Higashi Syndrome
title_sort oral management of a haematopoietic stem cell transplant recipient with chédiak–higashi syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476280/
https://www.ncbi.nlm.nih.gov/pubmed/34589239
http://dx.doi.org/10.1155/2021/9918199
work_keys_str_mv AT shimizukasumi oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome
AT hayashimiho oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome
AT itonozomi oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome
AT hamadakokoro oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome
AT koizumigaku oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome
AT kuroharakazuto oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome
AT arainaoya oralmanagementofahaematopoieticstemcelltransplantrecipientwithchediakhigashisyndrome

Ejemplares similares