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Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis
Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple masses on the scalp. Excisional biopsy was done and the mass revealed fascicles of smooth muscle fibers which show...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Society of Pathologists/The Korean Society for Cytopathology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476313/ https://www.ncbi.nlm.nih.gov/pubmed/34384147 http://dx.doi.org/10.4132/jptm.2021.06.23 |
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author | Lee, Jiyeon Cho, Yunjoo Choi, Kyue Hee Hwang, Inwoo Oh, Young Lyun |
author_facet | Lee, Jiyeon Cho, Yunjoo Choi, Kyue Hee Hwang, Inwoo Oh, Young Lyun |
author_sort | Lee, Jiyeon |
collection | PubMed |
description | Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple masses on the scalp. Excisional biopsy was done and the mass revealed fascicles of smooth muscle fibers which showed positive staining for smooth muscle actin, thus confirming the diagnosis of leiomyosarcoma. The patient was also found to have a 0.9 cm mass within the left thyroid. Fine-needle aspiration was done and the cytological smear showed hypercellular spindle cell clusters with hyperchromatic and large nuclei. Normal thyroid follicular cells were found within or around tumor cells. In this report, we present the cytologic findings of metastatic leiomyosarcoma to the thyroid and offer differential diagnoses of the aspirated spindle cells. |
format | Online Article Text |
id | pubmed-8476313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Society of Pathologists/The Korean Society for Cytopathology |
record_format | MEDLINE/PubMed |
spelling | pubmed-84763132021-10-07 Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis Lee, Jiyeon Cho, Yunjoo Choi, Kyue Hee Hwang, Inwoo Oh, Young Lyun J Pathol Transl Med Case Study Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple masses on the scalp. Excisional biopsy was done and the mass revealed fascicles of smooth muscle fibers which showed positive staining for smooth muscle actin, thus confirming the diagnosis of leiomyosarcoma. The patient was also found to have a 0.9 cm mass within the left thyroid. Fine-needle aspiration was done and the cytological smear showed hypercellular spindle cell clusters with hyperchromatic and large nuclei. Normal thyroid follicular cells were found within or around tumor cells. In this report, we present the cytologic findings of metastatic leiomyosarcoma to the thyroid and offer differential diagnoses of the aspirated spindle cells. The Korean Society of Pathologists/The Korean Society for Cytopathology 2021-09 2021-08-13 /pmc/articles/PMC8476313/ /pubmed/34384147 http://dx.doi.org/10.4132/jptm.2021.06.23 Text en © 2021 The Korean Society of Pathologists/The Korean Society for Cytopathology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Study Lee, Jiyeon Cho, Yunjoo Choi, Kyue Hee Hwang, Inwoo Oh, Young Lyun Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
title | Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
title_full | Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
title_fullStr | Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
title_full_unstemmed | Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
title_short | Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
title_sort | metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476313/ https://www.ncbi.nlm.nih.gov/pubmed/34384147 http://dx.doi.org/10.4132/jptm.2021.06.23 |
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