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Robust home brew fragment sizing assay for detection of MET exon 14 skipping mutation in non–small cell lung cancer patients in resource constrained community hospitals

BACKGROUND: A mutation/deletion involving donor or acceptor sites for exon 14 results in splicing out of exon 14 of the mesenchymal epithelial transition (MET) gene and is known as “MET exon 14 skipping” (ΔMET14). The two recent approvals with substantial objective responses and improved progression...

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Detalles Bibliográficos
Autores principales: Mehta, Anurag, Nathany, Shrinidhi, Chopra, Aanchal, Mattoo, Sakshi, Kumar, Dushyant, Panigrahi, Manoj Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476318/
https://www.ncbi.nlm.nih.gov/pubmed/34465078
http://dx.doi.org/10.4132/jptm.2021.07.15