Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target

BACKGROUND: Drug resistance and the lack of molecular therapeutic target are the main challenges in the management of osteosarcomas (OSs). Identification of novel genetic alteration(s) related with OS recurrence and chemotherapeutic resistance would be of scientific and clinical significance. METHOD...

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Detalles Bibliográficos
Autores principales: Nie, Jun-Hua, Yang, Tao, Li, Hong, Ye, Hai-Shan, Zhong, Guo-Qing, Li, Ting-Ting, Zhang, Chi, Huang, Wen-Han, Xiao, Jin, Li, Zhi, He, Jian-Li, Du, Bo-Le, Zhang, Yu, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476350/
https://www.ncbi.nlm.nih.gov/pubmed/34611509
http://dx.doi.org/10.1016/j.jbo.2021.100391

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