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Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells

Although effective drugs have been developed, including 5-fluorouracil (5-FU), advanced colorectal cancer (CRC) shows low therapeutic sensitivity resulting from the development of 5-FU resistance. Thymidylate synthase (TS) is a target protein of 5-FU, and elevated TS lowers the 5-FU sensitivity of C...

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Detalles Bibliográficos
Autores principales:	Yang, Changwon, Song, Jisoo, Hwang, Sunjae, Choi, Jungil, Song, Gwonhwa, Lim, Whasun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476449/ https://www.ncbi.nlm.nih.gov/pubmed/34562873 http://dx.doi.org/10.1016/j.redox.2021.102144

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