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TCF4 enhances hepatic metastasis of colorectal cancer by regulating tumor-associated macrophage via CCL2/CCR2 signaling

Colorectal cancer (CRC) liver metastasis is a significant clinical problem for which better therapies are urgently needed. Tumor-associated macrophage, a major cell population in the tumor microenvironment, is a known contributor to primary cancer progression and cancer metastasis. Here, we found TA...

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Detalles Bibliográficos
Autores principales: Tu, Wei, Gong, Jin, Zhou, Zhenzhen, Tian, Dean, Wang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476489/
https://www.ncbi.nlm.nih.gov/pubmed/34580284
http://dx.doi.org/10.1038/s41419-021-04166-w