Cargando…
TCF4 enhances hepatic metastasis of colorectal cancer by regulating tumor-associated macrophage via CCL2/CCR2 signaling
Colorectal cancer (CRC) liver metastasis is a significant clinical problem for which better therapies are urgently needed. Tumor-associated macrophage, a major cell population in the tumor microenvironment, is a known contributor to primary cancer progression and cancer metastasis. Here, we found TA...
Autores principales: | Tu, Wei, Gong, Jin, Zhou, Zhenzhen, Tian, Dean, Wang, Zhijun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476489/ https://www.ncbi.nlm.nih.gov/pubmed/34580284 http://dx.doi.org/10.1038/s41419-021-04166-w |
Ejemplares similares
-
Activated Hepatic Stellate Cells Induce Infiltration and Formation of CD163(+) Macrophages via CCL2/CCR2 Pathway
por: Xi, Sujuan, et al.
Publicado: (2021) -
Targeting the CCL2-CCR2 signaling axis in cancer metastasis
por: Lim, Su Yin, et al.
Publicado: (2016) -
Alveolar macrophages lack CCR2 expression and do not migrate to CCL2
por: Opalek, Judy M, et al.
Publicado: (2007) -
CCL2, CCR2 Gene Variants and CCL2, CCR2 Serum Levels Association with Age-Related Macular Degeneration
por: Gudauskiene, Gaile, et al.
Publicado: (2022) -
Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
por: Izumi, Kouji, et al.
Publicado: (2013)