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Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals

SARS-CoV-2 outbreak has been declared by World Health Organization as a worldwide pandemic. However, there are many unknowns about the antigen-specific T-cell-mediated immune responses to SARS-CoV-2 infection. Here, we present both single-cell TCR-seq and RNA-seq to analyze the dynamics of TCR reper...

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Detalles Bibliográficos
Autores principales: Luo, Lingjie, Liang, Wenhua, Pang, Jianfeng, Xu, Gang, Chen, Yingying, Guo, Xinrong, Wang, Xin, Zhao, Yi, Lai, Yangdian, Liu, Yang, Li, Bin, Su, Bing, Zhang, Shuye, Baniyash, Michal, Shen, Lei, Chen, Lei, Ling, Yun, Wang, Ying, Liang, Qiming, Lu, Hongzhou, Zhang, Zheng, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476510/
https://www.ncbi.nlm.nih.gov/pubmed/34580278
http://dx.doi.org/10.1038/s41421-021-00321-x