Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats

This study investigated whether oxidative and glycolytic rat skeletal muscles respond differently to a high-fat (HF) sucrose-enriched diet with respect to diacylglycerol (DAG) and ceramides accumulation, protein kinase C (PKC) activation, glucose metabolism, and the expression of inflammatory genes....

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Detalles Bibliográficos
Autores principales: Jani, Shailee, Da Eira, Daniel, Hadday, Ishvinder, Bikopoulos, George, Mohasses, Arta, de Pinho, Ricardo A., Ceddia, Rolando B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476522/
https://www.ncbi.nlm.nih.gov/pubmed/34580412
http://dx.doi.org/10.1038/s41598-021-98819-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476522/
https://www.ncbi.nlm.nih.gov/pubmed/34580412
http://dx.doi.org/10.1038/s41598-021-98819-7

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