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AGO CLIP-based imputation of potent siRNA sequences targeting SARS-CoV-2 with antifibrotic miRNA-like activity

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with fatal pulmonary fibrosis. Small interfering RNAs (siRNAs) can be developed to induce RNA interference against SARS-CoV-2, and their susceptible target sites can be inferred...

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Detalles Bibliográficos
Autores principales: Ahn, Seung Hyun, Gu, Dowoon, Koh, Yongjun, Lee, Hye-Sook, Chi, Sung Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476540/
https://www.ncbi.nlm.nih.gov/pubmed/34580386
http://dx.doi.org/10.1038/s41598-021-98708-z

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