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Altered microbiota by a high-fat diet accelerates lethal myeloid hematopoiesis associated with systemic SOCS3 deficiency

The suppressors of cytokine signaling (SOCS) proteins are negative regulators of cytokine signaling required to prevent excessive cellular responses. In particular, SOCS3 is involved in the regulation of metabolic syndromes, such as obesity and diabetes, by suppressing leptin and insulin signals. SO...

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Detalles Bibliográficos
Autores principales: Cho, Kaori, Ushiki, Takashi, Ishiguro, Hajime, Tamura, Suguru, Araki, Masaya, Suwabe, Tatsuya, Katagiri, Takayuki, Watanabe, Mari, Fujimoto, Yoko, Ohashi, Riuko, Ajioka, Yoichi, Shimizu, Ippei, Okuda, Shujiro, Masuko, Masayoshi, Nakagawa, Yoshimi, Hirai, Hideyo, Alexander, Warren S., Shimano, Hitoshi, Sone, Hirohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476681/
https://www.ncbi.nlm.nih.gov/pubmed/34611611
http://dx.doi.org/10.1016/j.isci.2021.103117