The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

OBJECTIVE: Sweet taste receptors (STR) are expressed in the gut and other extra-oral tissues, suggesting that STR-mediated nutrient sensing may contribute to human physiology beyond taste. A common variant (Ile191Val) in the TAS1R2 gene of STR is associated with nutritional and metabolic outcomes in...

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Detalles Bibliográficos
Autores principales: Serrano, Joan, Seflova, Jaroslava, Park, Jihye, Pribadi, Marsha, Sanematsu, Keisuke, Shigemura, Noriatsu, Serna, Vanida, Yi, Fanchao, Mari, Andrea, Procko, Erik, Pratley, Richard E., Robia, Seth L., Kyriazis, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476773/
https://www.ncbi.nlm.nih.gov/pubmed/34509698
http://dx.doi.org/10.1016/j.molmet.2021.101339

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