Cargando…
SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer
Secreted Ly6/uPAR-related protein 1 (SLURP-1) is a secreted Ly6/uPAR protein that negatively modulates the nicotinic acetylcholine receptor of α7 type (α7-nAChR), participating in control of cancer cell growth. Previously we showed, that a recombinant analogue of human SLURP-1 (rSLURP-1) diminishes...
Autores principales: | Bychkov, Maxim L., Shulepko, Mikhail A., Shlepova, Olga V., Kulbatskii, Dmitrii S., Chulina, Irina A., Paramonov, Alexander S., Baidakova, Ludmila K., Azev, Viatcheslav N., Koshelev, Sergey G., Kirpichnikov, Mikhail P., Shenkarev, Zakhar O., Lyukmanova, Ekaterina N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476798/ https://www.ncbi.nlm.nih.gov/pubmed/34595181 http://dx.doi.org/10.3389/fcell.2021.739391 |
Ejemplares similares
-
Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors
por: Bychkov, Maxim, et al.
Publicado: (2019) -
Human SLURP-1 and SLURP-2 Proteins Acting on Nicotinic Acetylcholine Receptors Reduce Proliferation of Human Colorectal Adenocarcinoma HT-29 Cells
por: Lyukmanova, E. N., et al.
Publicado: (2014) -
Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor
por: Lyukmanova, Ekaterina N., et al.
Publicado: (2016) -
Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer
por: Sudarikova, Anastasia V., et al.
Publicado: (2022) -
Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors
por: Lyukmanova, E. N., et al.
Publicado: (2016)